Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Turbulence at centimeter scales plays a pivotal role in shaping the overturning circulation of the deep ocean (1, 2), as well as the ocean’s capacity to distribute and store climate-critical tracers ...

High-resistant starch (RS)/low-glutelin sbeIIb/Lgc1 lines were generated by CRISPR-Cas9-induced site-specific mutations in SBEIIb in an elite low-glutelin japonica rice cultivar ().According to this ...

We demonstrate that substitutionally inert octahedral metal complexes, such as the iridium(III) carbene complex (1a), provide a useful source of potent inhibitors for unexplored oncogenic protein ...

Land use change is crucial to addressing the existential threats of climate change and biodiversity loss while enhancing food security [M. Zurek et al., Science 376, 1416–1421 (2022)].The ...

In eukaryotes, genomic DNA is packaged into chromatin, which is the substrate for transcription, DNA replication, repair, and recombination. Within chromatin, nucleosomes contain two copies of each of ...

In the secretory pathway, the pH within organelles is gradually acidified, starting at 7.1 to 7.2 in the endoplasmic reticulum, decreasing to 6.0 to 6.7 in the Golgi apparatus/trans-Golgi network ...

Cotyledon greening is a crucial process for seedlings to survive the dark-to-light transition during their soil emergence. While the complex strategies employed by etiolated seedlings to ensure ...

Among the characteristics shared by all extant living systems (1–3), their chemically controlled self-reproduction ranks perhaps as one of the most spectacular and exclusive.Under the control of their ...

Despite these successes, polyhydride synthesis remains challenging. For instance, it took nearly a decade to experimentally realize CaH 6 (12, 13) after its theoretical prediction ().A major hurdle is ...

Pigmentation plays a vital role in the survival of organisms, supporting functions such as camouflage, communication, and mate attraction. In vertebrates, these functions are mediated by specialized ...

Sorting cells with target metabolic functions from a mutant pool exhibiting substantial genetic diversity is often the rate-limiting step in synthetic biology. Here, we developed a label-free, ...