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The EMBO Journal1 lá
Targeted protein degradation in Escherichia coli using CLIPPERs
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. New, universal tools for targeted protein ...
EMBO Press2 lá
From microbes to molecules: unveiling host-microbe interactions with spatial metabolomics
Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...
The EMBO Journal3 lá
LRBA deficiency impairs autophagy and contributes to enhanced antigen presentation and T-cell dysregulation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
The EMBO Journal1y
The ER-SURF pathway uses ER-mitochondria contact sites for protein targeting to mitochondria - EMBO reports
We recently discovered that the binding of mitochondrial precursor proteins to the ER surface is not simply the result of an unavoidable mislocalization, but rather that the ER-to-mitochondria ...
The EMBO Journal3y
Coupling traction force patterns and actomyosin wave dynamics reveals mechanics of cell motion - Molecular Systems Biology
Motile cells can use and switch between different modes of migration. Here, we use traction force microscopy and fluorescent labeling of actin and myosin to quantify and correlate traction force ...
The EMBO Journal23 lá
Epigenetic regulation of neural stem cell aging in the mouse hippocampus by Setd8 downregulation
Neural stem cells (NSCs) in the mammalian brain decline rapidly with age, leading to impairment of hippocampal memory function in later life. However, the relationship between epigenetic remodeling ...
EMBO Press8 lá
Insights from human NF-κB knockouts
The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...
The EMBO Journal3 lá
Editorial Teams - EMBO Press
Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...
The EMBO Journal16 lá
CD206+ macrophages facilitate wound healing through interactions with
Macrophages not only clean the wound early for repair, but are also critically involved in all subsequent phases of proliferation and regeneration (Mirza et al, 2009; Shook et al, 2016).They ...
The EMBO JournalLíon na míonna: 8
Ageing-associated long non-coding RNA extends lifespan and reduces translation in non-dividing cells | EMBO reports
Genomes produce widespread long non-coding RNAs (lncRNAs) of largely unknown functions. We characterize aal1 (ageing-associated lncRNA), which is induced in quiescent fission yeast cells. Deletion of ...
The EMBO Journal1y
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor - EMBO Molecular Medicine
Physiological regulation of transgene expression is a major challenge in gene therapy. Onasemnogene abeparvovec (Zolgensma ®) is an approved adeno-associated virus (AAV) vector gene therapy for ...
The EMBO Journal21 lá
Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53 -mutant AML cells - EMBO Molecular Medicine
TP53-mutant acute myeloid leukemia (AML) and myelodysplastic neoplasms (MDS) are characterized by chemotherapy resistance and represent an unmet clinical need.Chimeric antigen receptor (CAR) T-cells ...