The 2024 campaign was a lost season for the San Francisco 49ers. Coming off a narrow, heartbreaking loss in Super Bowl LVIII, they were hoping to finally make good on their prolonged "Quest for Six," only to suffer a prolonged string of key injuries. As a result of those injuries, they went 6-11 and missed the playoffs.

No one on the 49ers had a rougher 2024 season than Christian McCaffrey. Now, with the 2025 season drawing ever nearer, the general public may not see the superstar back on the gridiron until the regular season begins Sept. 7.

Head coach Kyle Shanahan said that Patrick Taylor is set to miss multiple weeks with a dislocated shoulder and Corey Kiner is set to be out for a similar amount of time after suffering a high-ankle sprain. Jeff Wilson and Ke’Shawn Vaughn are the other backs on the roster at the moment.

A revitalized Christian McCaffrey took the ball on the 49ers’ opening play and was off and running in a heavy workload Thursday in a joint practice at the Las Vegas Raiders’ facility.

Christian McCaffrey already is prepared for Week 1. The All-Pro running back had a disappointing 2024 NFL season that was

Through just two preseason games, the 49ers already have four injured running backs -- Isaac Guerendo (shoulder), Patrick Taylor Jr. (shoulder), Jordan James (finger) and Corey Kiner (ankle). Their only healthy running backs currently are Christian McCaffrey, Jeff Wilson Jr. and Ke'Shawn Vaughn.

Won't take field Saturday

Christian McCaffrey’s wife, Olivia Culpo, gave her followers a glimpse into her life with a newborn. She posted a mirror selfie on her Instagram story on Wednesday, which showed her using a breast pump as she prepared bottles for her daughter.

Before the 49ers hit Las Vegas — or, specifically, the Raiders’ facility in Henderson — let’s address pressing questions from 49ers fans in this preseason mailbag.