Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Antibiotic resistance, especially in multidrug-resistant ESKAPE pathogens, remains a worldwide problem. Combination antimicrobial therapies may be an important strategy to overcome resistance and ...

High-resistant starch (RS)/low-glutelin sbeIIb/Lgc1 lines were generated by CRISPR-Cas9-induced site-specific mutations in SBEIIb in an elite low-glutelin japonica rice cultivar ().According to this ...

We demonstrate that substitutionally inert octahedral metal complexes, such as the iridium(III) carbene complex (1a), provide a useful source of potent inhibitors for unexplored oncogenic protein ...

Land use change is crucial to addressing the existential threats of climate change and biodiversity loss while enhancing food security [M. Zurek et al., Science 376, 1416–1421 (2022)].The ...

All species have an environmental niche, and despite technological advances, humans are unlikely to be an exception. Here, we demonstrate that for millennia, human populations have resided in the same ...

These questions also matter for fisheries and a sustainable pet trade. Without knowing which populations seed the most babies into the next generation, fishermen can’t know where is safe to cast nets ...

Astrocytes have a primary cell body (soma) with numerous branching processes that envelope nearby synapses ().This three-part structure is known as the tripartite synapse ().A single astrocyte can ...

Vetiver (Vetiveria zizanioides), native to Thailand and Java, is highly attractive to the rice stem borer (Chilo suppressalis, RSB), a major rice pest in Asia.As a result, it is widely used as an ...

Bispecific T cell engagers (TcEs) that are able to simultaneously bind to epitopes on cancer cells and T cells are a versatile, highly potent, and economical immunotherapeutic tool ().TcEs are ...

The mitochondrial antiviral signaling protein (MAVS) (also known as IPS1, VISA, or Cardif) serves as a key hub in innate immunity against RNA viruses, localizes to the mitochondrial outer membrane ...

The human brain produces complex spatiotemporal neural dynamics across multiple time and length scales. Abstracting the brain as a large-scale network of discrete interacting regions has proved ...