Faces in real life convey categorical attributes (e.g., age), unique identities, and dynamic information (e.g., expression, attention). Deep convolutional neural networks (DCNNs) can be trained to ...

Healthy brain function requires a delicate balance of neural excitation (E) and inhibition (I). In animals, this balance—the E/I ratio—is known to decrease with the maturation of inhibitory circuitry ...

Dysregulation of AMPA receptors (AMPARs) contributes to a number of neurological and psychiatric disorders, including AD. However, studying longitudinal AMPAR changes in AD animals has been a big ...

Sleep problems and intrusive memories play an important role in the onset and maintenance of many mental health disorders. Here, we show that depriving healthy participants of sleep disrupts their ...

Plants must actively regulate their growth to acclimate to stressful environments and optimize growth. Here, we describe a mechanism by which a root hair–specific response is important for salt ...

This work was supported by Ludwig Institute for Cancer Research core funding (Y.S.) and an endowed professorship by the Icahn School of Medicine at Mount Sinai (J.J.). This work utilized the NMR ...

Long-term light at night (LAN) exposure poses a health threat to nocturnal lab animals. Whether diurnal animals suffer the same deleterious effect imposed by LAN and how it works are still open ...

The first Global Stocktake of progress under the Paris Agreement issued a clear warning: Near-term global greenhouse gas (GHG) emissions trends are not aligned with modeled pathways consistent with ...

We developed a strategy to identify gut bacteria functionally linked to the development of multiple sclerosis (MS). To minimize confounders, we analyzed microbiota composition in a large cohort of ...

This paper introduces a single-step methodology for crafting soft millirobots capable of intricate multistep shape morphing in response to independently decoupled environmental stimuli. The unique ...

Peto’s paradox—the puzzling disconnect between body size and cancer prevalence across species—has long stood as one of comparative biology’s most captivating and unresolved enigmas. Through the ...

Koh et al. show that 15-hydroxyprostaglandin dehydrogenase (15-PGDH) is pathologically elevated in human and mouse Alzheimer’s disease (AD), traumatic brain injury (TBI), and aging, with 15-PGDH ...