Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...
The field of spatial transcriptomics utilizes technologies that map gene expression data to specific cellular locations within tissues. While traditional RNA sequencing methods generate quantitative ...
In multicellular organisms, each cell is influenced by the others in its surrounding environment, and the maintenance of cellular and tissue spatiality – or lack thereof – carries significant ...
This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.
Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...
A new software tool, ovrlpy, improves quality control in spatial transcriptomics, a key technology in biomedical research. Developed by the Berlin Institute of Health at Charité (BIH) in international ...